Calvin Ly

Graduate Student

Calvin received his B.S. in chemistry with an emphasis in biology from UC Merced.  He studied the role of oxidative stress in viral infections, specifically hepatitis C virus, under the guidance of Dr. Anand Singh and Dr. Seung Bum Park in the lab of Professor Jinah Choi.  Currently, Calvin is interested in developing cellular assays for studying the mechanisms of known cognitive enhancers as well as the development of novel neurotherapeutics.

Publications

• Ly, C.; Shimizu, A. J.; Vargas, M. V.; Duim, W. C.; Wender, P. A.; Olson, D. E. Bryostatin 1 Promotes Synaptogenesis and Reduces Dendritic Spine Density in Cortical Cultures Through a PKC-Dependent Mechanism. ACS Chem. Neurosci., 2020, 11, 1545–1554. 

• Dunlap, L. E.; Azinfar, A.; Ly, C.; Cameron, L. P.; Viswanathan, J.; Tombari, R. J.; Myers-Turnbull, D.; Taylor, J. C.; Grodzki, A. C.; Lein, P. J.; Kokel, D.; Olson, D. E. Identification of Psychoplastogenic N,N-Dimethylaminoisotryptamine (isoDMT) Analogs Through Structure-Activity Relationship Studies. J. Med. Chem., 2020, 63, 1142–1155. 

​•Ly, C.; Greb, A. C.; Cameron, L. P.; Wong, J. M.; Barragan, E. V.; Wilson, P. C.; Burbach, K. F.; Soltanzadeh Zarandi, S.; Sood, A.; Paddy, M. R.; Duim, W. C.; Dennis, M. Y.; McAllister, A. K.; Ori-McKenney, K. M.; Gray, J. A.; Olson, D. E. Psychedelics Promote Structural and Functional Neural Plasticity. Cell Reports 2018, 23, 3170–3182. 

Awards
Chemical Biology Training Grant Fellowship
UCLA Clinical and Translational Science Institute Poster Presentation (2nd Place)